Description
The Serotonin System: History, Neuropharmacology, and Pathology provides an up-to-date accounting on the physiology and pathophysiology of serotonin and the role it plays in behavioral functions. In addition, the book explores the potential roles of 5-HT1 in neurodevelopmental disorders and summarizes the history of the discovery and development of serotonergic drugs for the treatment of neuropsychiatric disorders. This concise, yet thorough, volume is the perfect introduction to this critical neurotransmitter. It is ideal for students and researchers new to the study of behavior, neuropsychiatry or neuropharmacology, but is also a great resource for established investigators who want a greater perspective on serotonin.
- Examines the role of serotonin in physiological functions and neuropsychiatric disorders
- Provides in-depth knowledge on all aspects of the serotonin system
- Explores serotonergic receptors as targets for both current and new therapeutic compounds
Table of Contents
1. The metabolism of indoleamines 2. Neurodevelopmental Roles and The Serotonin Hypothesis of Autism Spectrum Disorder 3. The role of serotonin receptors in the control of cardiovascular function 4. Serotonin Receptors Nomenclature 5. A perspective: from the serotonin hypothesis to cognitive neuropsychological approaches 6. Endocrine and genetic moderation of serotonin systems and the psychopathology of affective disorders 7. Serotonin and sexual behavior 8. Serotonin and cognitive flexibility 9. Serotonin and Aggression 10. Serotonin and Sleep 11. Serotonin and the Psychedelics 12. Serotonin and nociception: from nociceptive transduction at the periphery to pain modulation from the brain 13. Serotonin and Feeding Regulation 14. The outlook for the development of serotonergic drugs as therapeutic medications for psychiatric disorders
