Description
Polyphenols: Mechanisms of Action in Human Health and Disease, Second Edition describes the mechanisms of polyphenol antioxidant activities and their use in disease prevention. Chapters highlight the anti-inflammatory activity of polyphenols on key dendritic cells, how they modulate and suppress inflammation, and how they are inactivated or activated by metabolism in the gut and circulating blood. Polyphenols have proven effective for key health benefits, including bone health, organ health, cardiac and vascular conditions, absorption and metabolism, and cancer and diseases of the immune system. They are a unique group of phytochemicals that are present in all fruits, vegetables and other plant products.
This very diverse and multi-functional group of active plant compounds contain powerful antioxidant properties and exhibit remarkable chemical, biological and physiological properties, including cancer prevention and cardio-protective activities.
- Expands coverage on green tea, cocoa, wine, cumin and herbs
- Outlines their chemical properties, bioavailability and metabolomics
- Provides a self-teaching guide to learn the mechanisms of action and health benefits of polyphenols
Table of Contents
1. Polyphenols in the Prevention of Acute Pancreatitis in Preclinical Systems of Study: A Revisit
2. Polyphenols as Supplements in Foods and Beverages: Recent Discoveries and Health Benefits, an Update
3. Xanthohumol and the Medicinal Benefits of Beer
4. Polyphenolic Flavonoids and Metalloprotease Inhibition: Applications to Health and Disease
5. Biological and Pharmacological Effects of Polyphenolic Compounds From Ecklonia cava
6. Clerodendrum volubile: Phenolics and Applications to Health
7. Eryngium campestre L.: Polyphenolic and Flavonoid Compounds; Applications to Health and Disease
8. Antioxidant Activity of Anthocyanins in Common Legume Grains
9. Tomato Polyphenolics: Putative Applications to Health and Disease
10. Polyphenolic Compounds in Sweet Cherries: A Focus on Anthocyanins
11. Citrus Fruit Polyphenols and Flavonoids: Applications to Psychiatric Disorders
12. Anthocyanins and Diabetes Regulation
13. The Role of Direct and Indirect Polyphenolic Antioxidants in Protection Against Oxidative Stress
14. Role of Protocatechuic Acid in Obesity-Related Pathologies: An Update
15. Exposure to Polyphenolic Compounds Modulates Type 1 Diabetes: The Case of Genistein
16. Chocolate/Cocoa Polyphenols and Oxidative Stress
17. An Overview of Dietary Polyphenols and Their Therapeutic Effects
18. The Polyphenolic Compound Resveratrol Attenuates Pain: Neurophysiological Mechanisms
19. Possible Benefits and Risks of Polyphenols Supplementation During Pregnancy
20. Flavonoids as Modulators of Neutrophils’ Oxidative Burst: Structure-Activity Relationship
21. Manipulation of Mitochondrial Function by Polyphenols for New Treatment Strategies
22. Bioavailability of Flavonoids: The Role of Cell Membrane Transporters
23. Interaction of Polyphenols with the Intestinal and Placental Absorption of Some Bioactive Compounds
24. Analyzing Ingredients in Dietary Supplements and Their Metabolites
25. Metabolism of Dietary Polyphenols by Human Gut Microbiota and Their Health Benefits
26. Bioavailability and Biochemistry of Quercetin and Applications to Health and Diseases
27. Effects of Quercetin and Its Combinations on Health
28. Green Tea Polyphenols in the Amelioration of Osteoarthritis: Memoir on the Preclinical Observations
29. Polyphenolics Evoke Healing Responses: Clinical Evidence and Role of Predictive Biomarkers 403
30. Hepatoprotective Effects of Green Tea and Its Polyphenols: A Revisit
31. CAPE and Tympanosclerosis
32. The Polyphenolic Compound Hesperidin and Bone Protection
