Advanced Topics in Molecular Biology

Advanced Topics in Molecular Biology

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  • 製本 Hardcover:ハードカバー版/ページ数 152 p.
  • 言語 ENG,ENG
  • 商品コード 9781898486282
  • DDC分類 572

Table of Contents

Preface                                            vii
Organization of DNA in the Eukaryotic Genome
Introduction 1 (1)
Kinetic Analysis of Genome 2 (3)
Kinetic Classes of DNA 3 (1)
Non-Repetitive DNA (Functional DNA) 4 (1)
Repetitive DNA (Nonfunctional DNA) 4 (1)
Exons and Introns 5 (1)
Inverted Repeat Sequences 6 (3)
DNA Replication
Introduction 9 (2)
DNA Replication in Prokaryotes 11 (8)
Bacterial Replication 11 (3)
Origin of Replication and Creating the 14 (1)
Replication Fork
DNA Polymerases-The Enzymes Responsible 15 (1)
for DNA Synthesis
Okazaki Fragments and RNA Priming for DNA 16 (1)
Synthesis
Primosomes and Replisomes 17 (1)
Coordination Between Leading and Lagging 18 (1)
Strands of DNA
Termination of Replication 18 (1)
DNA Replication in Eukaryotes 19 (2)
Eukaryotic DNA Polymerases 19 (1)
DNA Replication in Eukaryotes 20 (1)
DNA Repair Mechanism 21 (3)
DNA Ligase 24 (1)
Reverse Transcriptase 25 (3)
DNA Methylation 28 (2)
DNA Topoisomerases 30 (1)
DNA Gyrase 31 (4)
Transcription
Introduction 35 (1)
Basic Aspects of Transcription 36 (5)
Transcription in Prokaryotes 41 (6)
E. coli RNA Polymerase 41 (1)
Sigma Factor 42 (1)
Initiation and Elongation of the RNA Chain 43 (1)
Termination of Transcription 44 (1)
Rho Factor 45 (1)
Psi Factor 46 (1)
The Promoter Concept 46 (1)
Transcription in Eukaryotes 47 (11)
Eukaryotic RNA Polymerases 50 (2)
Transcription by RNA Polymerase I 52 (1)
Transcription by RNA Polymerase II 53 (3)
Transcription by RNA Polymerase III 56 (1)
Termination of Eukaryotic Transcription 57 (1)
Inhibitors of Nucleic Acids Biosynthesis 58 (7)
RNA Splicing
Introduction 65 (2)
Nuclear Splicing 67 (3)
Spliceosome and Small Nuclear RNAs 70 (2)
Splicing Mechanism in Group I and Group II 72 (1)
Introns
Alternative Splicing 73 (2)
Cis-splicing and Trans-splicing Reactions 75 (1)
tRNA Splicing 75 (4)
Translation
Introduction 79 (1)
Messenger RNA 80 (4)
mRNA Processing in Eukaryotes 81 (1)
Capping of Eukaryotic mRNA 81 (1)
Methylation of Internal Adenine Residues 82 (1)
of mRNA
Polyadenylation 82 (1)
RNA Splicing 83 (1)
Transport of Processed mRNA to the 84 (1)
Cytoplasm
tRNA and tRNA Synthetase 84 (4)
Transfer RNA (tRNA) 84 (2)
Activation of Amino Acids to Form 86 (2)
Aminoacyl tRNAs
Ribosome Structure 88 (3)
Ribosome Subunit Assembly 90 (1)
Factors Needed for Protein Synthesis 91 (1)
Initiation of Translation 92 (3)
Initiation of Peptide Chain in Bacteria 93 (1)
Initiation of Peptide Chain in Eukaryotes 94 (1)
Elongation of Peptide Chain 95 (1)
Termination of Translation 96 (1)
Accuracy of Translation 96 (1)
Post-translational Modifications 97 (1)
Inhibitors of Translation 97 (3)
Biosynthesis of Gramicidin-S 100(3)
Control of Gene Expression in Prokaryotes
Introduction 103(1)
Induction and Repression 104(2)
The Operon 106(1)
The Lactose Operon (Lac Operon) 106(3)
The Tryptophan Operon (Trp Operon) 109(2)
Attenuation 111(1)
Positive and Negative Control 112(1)
The Arabinose Operon (Ara Operon) 113(1)
Catabolite Repression 113(2)
Regulation of Gene Expression in Eukaryotes
Introduction 115(1)
Transcriptional Regulation of Eukaryotic 116(2)
Gene Expression
Post-Transcriptional Regulation of Gene 118(1)
Expression
Regulation of Gene Expression and RNA 118(1)
Processing
Other Mechanisms for Regulation of 119(2)
Eukaryotic Gene Expression
Transposable Elements
Introduction 121(1)
Bacterial Transposable Elements 122(2)
Eukaryotic Transposable Elements 124(5)
Transposons in Yeast 126(1)
Transposons in Drosophila 126(1)
Transposons in Animals and Humans 127(1)
Transposons in Maize 128(1)
Mechanisms of Transposition 129(3)
Applications of Transposons in Molecular 132(3)
Biology
Glossary 135(12)
Index 147