Description
Translational Autoimmunity: Treatment of Autoimmune Diseases, Volume Two in the Translational Immunology series, focuses on advances in therapeutic modalities in autoimmune diseases. Efficacy and safety of not only the current biologic therapies, but also novel drug targets are discussed. Therapeutic targeting of B regulatory cells, T regulatory cells, as well as the immunomodulation effects of nanoparticles and organisms are also covered, along with our understanding and future challenges of prognostic significance of treatments in autoimmune diseases.
- Covers the clinical aspects and treatment of autoimmunite diseases
- Meets the needs of basic scientists, clinicians and translational scientists and industry partners
- Mentions each and every key concept after background is drawn
- Supported by a systematic appraisal of the most recent evidence
- Helps students at all academic levels, but is also applicable to scientists who work with autoimmunity
Table of Contents
1. Introduction on therapeutic opportunities for autoimmunity 2. Innate lymphoid cells as therapeutic targets in autoimmune diseases 3. B regulatory cells in patients with autoimmune diseases: pathogenic significance, therapeutic potential 4. Regulatory T cells in autoimmunity and potential therapeutic targets 5. Application of IL-6 antagonists in autoimmune disorders 6. The search for monomer interaction-based alternative TNFa therapies 7. Generation of thymic cells from pluripotent stem cells for basic research and cell therapy 8. The NLRP3 inflammasome pathway in autoimmune diseases: a chronotherapeutic perspective? 9. Plasmocytes infiltrating autoimmune organs and their putative targeting 10. Biological aging and autoimmunity 11. Efficacy and safety of biologic treatment in autoimmune diseases 12. Nutritional implications for the pathophysiology and treatment of autoimmune disorders 13. Dysbiosis and probiotic applications in autoimmune diseases 14. Precision medicine in managing chronic conditions with an immunological component 15. New advanced therapy medicinal products in treatment of autoimmune diseases 16. Targeting of autoimmune disorders through metal nanoformulation in overcoming the fences of conventional treatment approaches 17. Immunomodulatory effects of parasites on autoimmunity 18. Prediction of autoimmune diseases: from bench to bedside
