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Description
This detailed, practical textbook focuses on immune mediated disorders of the nervous system with particular focus on systemic autoimmune disorders. Divided into three sections, the first discusses the neuroanatomical and pathophysiologic basis of immune mediated disorders of the nervous system. Following this are 25 chapters devoted to individual clinical conditions. To conclude, the final section explains what is known about the mechanisms of immunomodulatory treatments and practical points about monitoring patients on these treatments.
Neurorheumatology: A Comprehensive Guide to Immune Mediated Disorders of the Nervous System bridges the gaps among different branches of medicine and is an indispensable resource for rheumatologists and neurologists looking to develop a firm understanding of these dynamic disorders
Table of Contents
I. Physiology and Testing
The central and peripheral nervous system
Inflammation in the nervous system
Signs and symptoms of relevant rheumatological disorders
Imaging
Laboratory testing
Electrophysiological studies
Biopsy
II. Diseases and their Nervous System Effects
Systemic Lupus Erythematosus
Antiphospholipid and thrombotic microangiopathies
Sjögren Syndrome
Rheumatoid ArthritisSarcoidosis
Seronegative spondyloarthropathy
IgG4-Related Disease
Scleroderma
Giant Cell Arteritis
CNS vasculitis
Neuro-Behҫet Disease
Autoinflammatory Diseases
Ocular + Auditory Inflammatory Syndromes
Paraneoplastic Syndromes
Neuronal Surface Antibody-Mediated Autoimmune Encephalitis
Hashimoto’s encephalopathy/SREAT
Celiac Disease
Neuromyelitis Optica
Multiple sclerosis and relation to systemic autoimmune disordersStiff-person Syndrome
Inflammatory myopathies
Neuromuscular Junction Disorders
Peripheral neuropathy in rheumatologic disorders, plexopathy
Chronic Fatigue Syndrome/Systemic Exertion Intolerance Disease
Lyme Disease
Complications related to pharmacotherapy
Amyloidosis
III. Guide to Rheumatological Diagnosis and Tests by Syndrome –
Clinical syndrome tables
Differential diagnoses
IV. Overview of immunomodulatory treatment paradigms
Corticosteroids
Oral steroid-sparing agents
Cyclophosphamide
Biologics
IVIG
Plasmapheresis
