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基本説明
Describes the design, synthesis, assembly and characterization, and the bio-(medical) application of interfacial layers on solid substrates with molecularly or supra-molecularly controlled architectures.
Full Description
The design and synthesis of molecularly or supramolecularly defined interfacial architectures have seen in recent years a remarkable growth of interest and scientific research activities for various reasons. On the one hand, it is generally believed that the construction of an interactive interface between the living world of cells, tissue, or whole organisms and the (inorganic or organic) materials world of technical devices such as implants or medical parts requires proper construction and structural (and functional) control of this organism-machine interface. It is still the very beginning of generating a better understanding of what is needed to make an organism tolerate implants, to guarantee bidirectional communication between microelectronic devices and living tissue, or to simply construct interactive biocompatibility of surfaces in general.
This exhaustive book lucidly describes the design, synthesis, assembly and characterization, and bio-(medical) applications of interfacial layers on solid substrates with molecularly or supramolecularly controlled architectures. Experts in the field share their contributions that have been developed in recent years.
Contents
Self-Assembled Monolayers (SAMs). Multi-Valent Chelator SAMs. Gemini SAMs. PEG SAMs. Electrochemically Designed SAMs. Polymer Brushes. Ultra-Sensitive Biosensing with Polymer Brushes. Noncovalent Anchoring of Proteins to Surfaces. S-Layer Proteins. Heparan Sulfate Surfaces to Probe the Functions of the Master Regulator of the Extracellular Space. Hemocompatible Surfaces. Peptide Nanotube Coatings for Bioapplications. Proteoglycanylated Surfaces. Surface-Attached Polymeric Hydrogel Films. Evanescent Wave Biosensors with Hydrogels Binding Matrix. IPNs. Biofunctional Grafted Dendrons. Glucase Biosensors: Transduction Method, Redox Materials, and Bio-Interface. Modification of Glass Surfaces by Phosphorus Dendrimer Layers for Biosensors. Tethering Lipid Bilayers to Solid Supports. In vitro Synthesis of Membrane Proteins. Integrin-Functionalized Artificial Membranes as Test Platforms for Monitoring Small Integrin Ligand Binding by Surface Plasmon-Enhanced Fluorescence Spectroscopy. Wetting of Surfaces by Lipid Bilayers. Patterned Lipid Bilayers on Solid Substrate as a Model System of the Biological Membrane. Electrically Addressable, Biologically Relevant Surface Supported Bilayers. Nanopatterning of Biomolecules by Dip Pen Lithography. Surfaces for Stem Cell Propagation. Mechanical Cues for Cell Culture. Constructing Defined Networks of Neurons. Mineralization on a Biomimetic Surface.MO-CVD on patterned SAMs. Application of Biofunctional Surfaces in Medical Diagnostics. Nanopatterning for Bioapplications.
