Genetic Factors in Drug Therapy : Clinical and Molecular Pharmacogenetics

  • ポイントキャンペーン

Genetic Factors in Drug Therapy : Clinical and Molecular Pharmacogenetics

  • ただいまウェブストアではご注文を受け付けておりません。 ⇒古書を探す
  • 製本 Hardcover:ハードカバー版/ページ数 657 p.
  • 言語 ENG
  • 商品コード 9780521412964
  • DDC分類 615.7

Table of Contents

Preface
Part I. Introduction: 1. The arrangement of the
information in this volume
2. General introduction
3. Classification of pharmacogenetic phenomena
Part II. Cytochrome P450 Based Phenomen: 4.
Cytochrome P450 - general features
5. Artlhydrocarbon hydroxylase (cytochrome P450
1A1 and 1A2)
6. The mephenytoin hydroxylation polymorphism
(cytochrome P450 2C18)
7. The debrisoquine/sparteine polymorphism
(cytochrome P450 2D6)
8. The cytochrome P450 3A subfamily
9. Tolbutamide
10. Phenytoin
11. Some other drugs of special interest
12. Cytochrome P450 reductase
13. General conclusions
Part III. Cholinesterase: 14. Cholinesterase
Part IV. Alcohol and Alcoholism: 15. Alcohol
and alcoholism
Part V. N-Acetyltransferase: 16.
N-Acetyltransferase
Part VI. Miscellaneous Phase II Reactions
Showing Genetic Variability in Drug Metabolism:
17. The glucosidation of amobarbital
18. Glucuronosyltransferases
19. Glutathione-S-transferase
20. Methylation reactions
21. Paraoxonase
22. Sulphotransferases
23. Sulphoxidation deficiency
24. Halothane hepatitis and other topics
Part VII. Glucose-6-Phosphate Dehydrogenase
Deficiency: 25. Glucose-6-phosphate
dehydrogemase deficiency
Part VIII. The Hepatic Porphyrias: 26. The
hepatic porphyrias
Part IX. Malignant Hyperthermia: 27. Malignant
hyperthermia
Part X. Miscellaneous Systems Showing Genetic
Variability in Response to Drugs
28. Chlorpropamide-alcohol flushing
29. Glucocorticosteroids and intraocular
pressure
30. Unstable haemoglobins
31. Human lymphocyte antigens and adverse
reactions to drugs
32. The polymorphism for tasting
phenylthiocarbamide (PTC syn phenylthiourea)
33. Hereditary anticoagulant resistance
34. NADH-cytochrome b5 reductase
35. Catalase
36. Antibiotic-induced deafness,
chloramphenicol toxicity and other topics
Part XI. Polygenic Effects in Pharmacogenetics:
37. Polygenic effects in pharmacogenetics
Part XII. Common Themes: 38. Common themes
Part XIII. Conclusions: 39. Conclusions
Part XIV. Appendices: Index.