There is now firm evidence that a non-genetically determined event plays a major role in the aetiology of insulin dependent diabetes mellitus (IDDM), and that this event is due to exposure to an environmental agent. While genetic factors are more important in the pathogenesis of non-insulin dependent diabetes mellitus (NIDDM), environmental factors also play a major role. This study provides a comprehensive assessment of the uses of NIDDM and IDDM and pays particular attention to the environmental factors involved in disease pathogenesis. The identification of these factors opens the way for therapeutic trials aimed at preventing, even curing, this potentially devastating disease.
Table of Contents
PARTIAL TABLE OF CONTENTS: Partial table of
INSULIN-DEPENDENT DIABETES MELLITUS.
Genetic Causes of Insulin- Dependent Diabetes
Mellitus (D. Cavan & A. Barnett).
Population Studies (N. Tajima, et al.).
Diabetic Twin Studies (R. Leslie).
The Role of Toxins (R. Assan & E. Larger).
Environmental Factors in Pregnancy and
Infancy Influencing Insulin-Dependent
Diabetes Mellitus (R. Elliot).
NON-INSULIN-DEPENDENT DIABETES MELLITUS.
The Genetic Aspects of Non-Insulin-Dependent
Diabetes Mellitus (M. McCarthy & G. Hitman).
Family Studies: Perspectives on the Genetic
and Environmental Determinants of
Non-Insulin-Dependent Diabetes Mellitus (J.
Cook & R. Turner).
Thrifty Genotypes (P. Zimmet & K. O'Dea).
Syndrome X (M. Walker & K. Alberti).